From 2893caa92a1f2f74969871148810033d07f5bbff Mon Sep 17 00:00:00 2001 From: MahdiAll99 <48736765+MahdiAll99@users.noreply.github.com> Date: Thu, 24 Sep 2026 16:29:53 +0000 Subject: [PATCH] feat(publications): add Simpler Radiomics Can Be Enough: Identifying the Minimal Feature Complexity Required for Accurate Prediction --- ...y-required-for-accurate-prediction-2026.md | 28 +++++++++++++++++++ src/data/publications.json | 10 +++++++ 2 files changed, 38 insertions(+) create mode 100644 src/content/publications/simpler-radiomics-can-be-enough-identifying-the-minimal-feature-complexity-required-for-accurate-prediction-2026.md diff --git a/src/content/publications/simpler-radiomics-can-be-enough-identifying-the-minimal-feature-complexity-required-for-accurate-prediction-2026.md b/src/content/publications/simpler-radiomics-can-be-enough-identifying-the-minimal-feature-complexity-required-for-accurate-prediction-2026.md new file mode 100644 index 0000000..3c4c8ef --- /dev/null +++ b/src/content/publications/simpler-radiomics-can-be-enough-identifying-the-minimal-feature-complexity-required-for-accurate-prediction-2026.md @@ -0,0 +1,28 @@ +## Date + +2026-08-07 + +## Authors + +- [Mahdi Loutfi](/team/mahdi-loutfi) +- [Martin Vallières](/team/martin-vallieres) + +## Summary + +**Purpose**: Clinical translation of radiomics is hindered by the high-dimensional feature sets and lack of accessible tools for clinicians. MEDiml, an open-source platform designed to help democratize the development of radiomics models by identifying the simplest predictive features through both a code-based and graphical interface. + +**Methods**: MEDiml was evaluated using 89,714 features from five oncological datasets (n=2,104). Tasks included histology subtype prediction for non-small cell lung cancer (NSCLC, MRI); renal cell carcinoma (RCC, MRI); and RCC (contrast-enhanced CT); IDH1 mutation prediction for low-grade glioma (LGG, MRI); and grade prediction for meningioma (MRI). For modeling, features are categorized by complexity (morphological, intensity, texture, linear/nonlinear filters) for XGBoost training. The pipeline cleans invariants and filters collinearity, retaining only features highly correlated with clinical endpoints. + +**Results**: We released the MEDiml software with detailed documentation (mediml.app). Evaluation demonstrated that maximum predictive performance does not always require high-complexity features. Optimal levels were: morphological for LGG-IDH1 and Meningioma-grading; intensity in NSCLC and RCC -CECT; and texture for RCC-MRI. In the RCC-CECT cohort, optimizing the re-segmentation range, a parameter for excluding non-target voxels affecting intensity features, improved performance from an AUC of 0.82 to 0.86. + +**Conclusion**: MEDiml successfully identifies the "optimal complexity level" for specific clinical outcomes, demonstrating that simpler models can often match or exceed the performance of high-dimensional sets. By providing an interactive, user-friendly interface and a strategy for feature minimization, MEDiml lowers the barrier to entry for clinicians, providing a scalable pathway for the clinical integration of radiomic biomarkers. + +## Links + +- [Primary link](NA) + +## BibTeX + +```bibtex + +``` diff --git a/src/data/publications.json b/src/data/publications.json index 6a93d39..4671c73 100644 --- a/src/data/publications.json +++ b/src/data/publications.json @@ -20,6 +20,16 @@ "type": "Journal Papers", "date": "2026-02-25" }, + { + "title": "Simpler Radiomics Can Be Enough: Identifying the Minimal Feature Complexity Required for Accurate Prediction", + "slug": "simpler-radiomics-can-be-enough-identifying-the-minimal-feature-complexity-required-for-accurate-prediction-2026", + "contributors": ["Mahdi Loutfi", "Martin Vallières"], + "journal": "Lady Davis Institute (LDI) Conference (Poster Presentation)", + "link": "NA", + "markdown": "publications/simpler-radiomics-can-be-enough-identifying-the-minimal-feature-complexity-required-for-accurate-prediction-2026.md", + "type": "Presentations", + "date": "2026-08-07" + }, { "title": "Kaféfak Presentation - First Publication Award", "slug": "kafefak-presentation-first-publication-award-2026",