diff --git a/src/managers/builtin/utils.ts b/src/managers/builtin/utils.ts
index dc44fe75..26a35ca2 100644
--- a/src/managers/builtin/utils.ts
+++ b/src/managers/builtin/utils.ts
@@ -185,12 +185,18 @@ export async function refreshPythons(
 
 const PIP_LIST_TIMEOUT_MS = 30_000;
 
+function getUvEnvironmentTarget(environment: PythonEnvironment): string {
+    // A virtual environment's executable may resolve to its base interpreter. uv accepts
+    // the environment directory directly, which preserves the environment boundary.
+    return environment.environmentPath.fsPath;
+}
+
 async function execPipList(environment: PythonEnvironment, log?: LogOutputChannel, args?: string[]): Promise<string> {
     // Use environmentPath directly for consistency with UV environment tracking
     const useUv = await shouldUseUv(log, environment.environmentPath.fsPath);
     if (useUv) {
         return await runUV(
-            ['pip', 'list', '--python', environment.execInfo.run.executable, '--format=json', ...(args ?? [])],
+            ['pip', 'list', '--python', getUvEnvironmentTarget(environment), '--format=json', ...(args ?? [])],
             undefined,
             log,
             undefined,
@@ -258,7 +264,7 @@ export async function refreshPipDirectPackageNames(
     const useUv = await shouldUseUv(log, environment.environmentPath.fsPath);
     if (useUv) {
         const treeOutput = await runUV(
-            ['pip', 'tree', '--python', environment.execInfo.run.executable, '--depth=0'],
+            ['pip', 'tree', '--python', getUvEnvironmentTarget(environment), '--depth=0'],
             undefined,
             log,
             undefined,
@@ -287,7 +293,7 @@ export async function managePackages(
     if (options.uninstall && options.uninstall.length > 0) {
         if (useUv) {
             await runUV(
-                [...uninstallArgs, '--python', environment.execInfo.run.executable, ...options.uninstall],
+                [...uninstallArgs, '--python', getUvEnvironmentTarget(environment), ...options.uninstall],
                 undefined,
                 manager.log,
                 token,
@@ -313,7 +319,7 @@ export async function managePackages(
 
         if (useUv) {
             await runUV(
-                [...installArgs, '--python', environment.execInfo.run.executable, ...processedInstallArgs],
+                [...installArgs, '--python', getUvEnvironmentTarget(environment), ...processedInstallArgs],
                 undefined,
                 manager.log,
                 token,
diff --git a/src/test/managers/builtin/packageManagement.unit.test.ts b/src/test/managers/builtin/packageManagement.unit.test.ts
new file mode 100644
index 00000000..8360bcf3
--- /dev/null
+++ b/src/test/managers/builtin/packageManagement.unit.test.ts
@@ -0,0 +1,101 @@
+import assert from 'assert';
+import * as path from 'path';
+import * as sinon from 'sinon';
+import * as typeMoq from 'typemoq';
+import { LogOutputChannel, Uri } from 'vscode';
+import { PackageManager, PythonEnvironment } from '../../../api';
+import * as helpers from '../../../managers/builtin/helpers';
+import {
+    managePackages,
+    refreshPipDirectPackageNames,
+    refreshPipPackages,
+} from '../../../managers/builtin/utils';
+import { createMockLogOutputChannel, setupNonThenable } from '../../mocks/helper';
+
+suite('Pip package management', () => {
+    let environment: typeMoq.IMock<PythonEnvironment>;
+    let manager: typeMoq.IMock<PackageManager>;
+    let log: LogOutputChannel;
+    let runUvStub: sinon.SinonStub;
+    let environmentTarget: string;
+    let baseInterpreter: string;
+
+    setup(() => {
+        environmentTarget = Uri.file(path.join('test-data', 'pipenv-environment')).fsPath;
+        baseInterpreter = Uri.file(path.join('test-data', 'uv', 'python')).fsPath;
+
+        environment = typeMoq.Mock.ofType<PythonEnvironment>();
+        environment.setup((env) => env.version).returns(() => '3.13.0');
+        environment.setup((env) => env.environmentPath).returns(() => Uri.file(environmentTarget));
+        environment.setup((env) => env.execInfo).returns(() => ({ run: { executable: baseInterpreter } }));
+        setupNonThenable(environment);
+
+        log = createMockLogOutputChannel();
+        manager = typeMoq.Mock.ofType<PackageManager>();
+        manager.setup((packageManager) => packageManager.log).returns(() => log);
+        setupNonThenable(manager);
+
+        sinon.stub(helpers, 'shouldUseUv').resolves(true);
+        runUvStub = sinon.stub(helpers, 'runUV').resolves('');
+    });
+
+    teardown(() => {
+        sinon.restore();
+    });
+
+    test('uses the environment path when listing packages with uv', async () => {
+        runUvStub.resolves('[]');
+
+        const packages = await refreshPipPackages(environment.object, log);
+
+        assert.deepStrictEqual(packages, []);
+        sinon.assert.calledWithExactly(
+            runUvStub,
+            ['pip', 'list', '--python', environmentTarget, '--format=json'],
+            undefined,
+            log,
+            undefined,
+            30_000,
+        );
+        assert.ok(!runUvStub.calledWith(sinon.match.array.contains([baseInterpreter])));
+    });
+
+    test('uses the environment path when finding direct packages with uv', async () => {
+        await refreshPipDirectPackageNames(environment.object, log);
+
+        sinon.assert.calledWithExactly(
+            runUvStub,
+            ['pip', 'tree', '--python', environmentTarget, '--depth=0'],
+            undefined,
+            log,
+            undefined,
+            30_000,
+        );
+        assert.ok(!runUvStub.calledWith(sinon.match.array.contains([baseInterpreter])));
+    });
+
+    test('uses the environment path when installing and uninstalling packages with uv', async () => {
+        await managePackages(
+            environment.object,
+            { install: ['absl-py'], uninstall: ['setuptools'] },
+            manager.object,
+        );
+
+        sinon.assert.calledTwice(runUvStub);
+        sinon.assert.calledWithExactly(
+            runUvStub.firstCall,
+            ['pip', 'uninstall', '--python', environmentTarget, 'setuptools'],
+            undefined,
+            log,
+            undefined,
+        );
+        sinon.assert.calledWithExactly(
+            runUvStub.secondCall,
+            ['pip', 'install', '--python', environmentTarget, 'absl-py'],
+            undefined,
+            log,
+            undefined,
+        );
+        assert.ok(!runUvStub.calledWith(sinon.match.array.contains([baseInterpreter])));
+    });
+});