genome-engineering

A verification and grounding layer for AI-driven genome writing. Foundation models and a grounded co-scientist agent propose edits; PEN-STACK checks each against validated tools, never a language model: where a write is safe and durable, which enzyme makes it, and where it goes off-target. Calibrated, provenance-tracked, pre-registered.

Open-source DNA design, cloning, validation, and bioinformatics workbench with a modern web UI and real-world training.

Two halves of one question: a pre-order verifier that re-derives requested edits from an exported DNA sequence and the GRCh38 reference alone and holds the order until it can, plus an ADMET property layer on scaffold splits. What was tried and did not ship is published too.

This repository contains the script written for PPR assembly automation with an OT2 system.

PROpeg — precision-optimized pegRNA design and structure visualization tool for plant prime editing (ICAR-CRRI & ICAR-IASRI)

This repo contains computational analysis performed in Li21.

Pearlbio — independent third-party profile of a public API surface, by API Evangelist. Pearl Bio is a synthetic biology company developing next-generation biomaterials for smart biologics. Its proprietary platform unites genome and ribosome engineering to produce novel biologics with diverse chemistries previously inaccessible, creating template-di

eGenesis — independent third-party profile of a public API surface, by API Evangelist. eGenesis is a biotechnology company working at the intersection of genome engineering and transplantation to make organ transplants accessible to all. Using a multiplex CRISPR gene-editing and genome-engineering platform, eGenesis engineers porcine (pig) donor or