Contract-first scientific computing and human-in-the-loop discovery across MCP, UAG, simulation and interactive runtimes.
GitHub Organization · Public State & Project Site · IP & Evidence Registry · Canonical Architecture
qFoldIT is a scientific mission platform that converts research and industrial objectives into governed, executable and auditable human/AI missions.
The platform separates scientific authority from presentation, gameplay, learning and commercial policy:
Scientific / Industrial Objective
↓
Mission Contract
↓
Capability Profile
↓
Mission Router
↓
Mission Compiler
↓
UAG / Scientific Object Model
↓
Runtime Adapter
↓
Human + AI Search
↓
Submission / Event
↓
CAMEO Reconciliation
↓
Scientific Validation
↓
Evidence / Contribution Record
↓
STATE Projection
↓
Enterprise Deliverable
The result is not merely a game level. It is a validated scientific workflow that can be rendered as an interactive experience when that is the best interface for the mission.
qFoldIT is designed to operate as a scientific capability fabric for MCP-compatible agents, including Claude-based research workflows.
The correct boundary is:
Claude / Scientific Agent
↓
MCP Scientific Tools & Services
↓
qFoldIT Mission Contract
↓
UAG / Scientific Object Model
↓
Mission Compiler / Runtime Adapter
↓
Execution
↓
Scientific Validator
Claude is an orchestration and reasoning interface. Scientific truth remains external to the conversational layer and is established by the configured scientific validators and customer-authorized reference boundaries.
qFoldIT therefore does not claim that an LLM response is itself a scientific result, nor that an interactive runtime can redefine scientific authority.
| Layer | Function | Representative qFoldIT surfaces |
|---|---|---|
| Governance | Rights, provenance, contracts, evidence | .github, .github-private, IP-valuation-registry |
| Enterprise Control Plane | Customer objectives and mission lifecycle | CORPORATE_APP |
| Compilation | Routing and deterministic mission compilation | CORPORATE_APP, conformance fixtures |
| Scientific Object Model | Canonical scientific/world representation | Scientific-Object-Schema, UAG |
| Scientific MCP Mesh | Machine-readable tools and agents | qFold-MCP, Protein-MCP, Protein-Design-MCP, Atomic-MCP, scientific skills |
| Validation Fabric | Authoritative scientific scoring | OPENSTRUCTURE, domain validators, quantum services |
| Reconciliation | Runtime submission → scientific evidence | CAMEO-REALTIME-VALIDATION, INDUSTRIAL-CAMEO |
| Runtime Mesh | Engine/browser/desktop execution | UEFN, Unity, UNIGINE, Web, Standalone |
| Learning | Strategy/coaching/compute optimization | learning-policy, gameplay optimization, QOS |
| Attention / Presentation | Participation and distribution | original/licensed narrative and game layers |
| Commercial Policy | Eligibility, rights, rewards and customer policy | enterprise policy layer |
| STATE | Safe public/organizational projection | qfoldit.github.io |
The organization is moving toward explicit, versioned boundaries rather than direct application-to-engine coupling.
qfoldit.mission/1.0
qfoldit.mission-routing/1.0
qfoldit.mission-compiled/1.0
qfoldit.uag/0.1
qfoldit.event/1.0
qfoldit.submission/1.0
qfoldit.evidence/1.0
qfoldit.learning-policy/1.0
These contracts let scientific services, enterprise applications, game engines, simulation environments and future runtimes evolve independently.
One scientific representation can be delivered through multiple interaction surfaces:
Canonical UAG / Scientific State
│
┌─────────────────────┼─────────────────────┐
│ │ │
UEFN Unity UNIGINE
│ │ │
UEFN-TOOLBELT UNITY-TOOLBELT UNIGINE-TOOLBELT
│ │ │
└─────────────────────┼─────────────────────┘
│
WEB-TOOLBELT
│
STANDALONE APP
Runtime adapters are execution surfaces, not scientific authorities. The Web runtime intentionally consumes canonical state rather than embedding heavyweight scientific solvers; the Standalone runtime provides an offline-first desktop experience with local interaction and MCP bridging. Existing adapter work explicitly tracks third-party licenses and attribution.
qFoldIT's current OpenStructure integration establishes a server-side scientific validation boundary with protected references and native structural scoring.
CORPORATE_APP
↓ authenticated server-side request
OPENSTRUCTURE qFoldIT service
↓
OpenStructure / `ost`
↓
LDDT / local-LDDT / QS-score
↓
ValidationResult
↓
validation.completed + audit evidence
A failed validator does not become a score by fallback logic. This fail-closed rule is fundamental to the qFoldIT evidence model.
qFoldIT distinguishes:
- Authoring clock — target creation and mission compilation.
- Runtime clock — interaction and event capture.
- Reconciliation clock — external scientific validation and evidence publication.
For UEFN this distinction is essential: live Verse execution is not treated as a direct arbitrary-network scientific client. The intended model is runtime interaction → session publication → external reconciliation → scientific validation.
qFoldIT treats players and agents as search participants rather than as sources of scientific truth.
Mission State
+ Player / Agent State
+ Historical Outcomes
+ Compute State
↓
Learning Policy
↓
Decision / Coaching
↓
Runtime Outcome
↓
Validation
↓
Evidence
↓
Policy Update
The target metric is validated scientific contribution density, not raw playtime.
Game design, narrative, cultural presentation and interactive distribution are first-class platform capabilities, but they remain downstream of mission and scientific authority:
Original / Licensed Presentation
↓
Quest Object
↓
Scientific Mission
↓
Human Search
↓
Validation
↓
Contribution
Third-party brands, entertainment franchises and external ecosystems remain governed by their own licenses and contracts. qFoldIT does not claim ownership of upstream or partner IP merely by integrating with it.
qFoldIT's mission architecture is designed for:
- protein and peptide design;
- structural biology and molecular modeling;
- drug discovery and ADMET;
- synthetic biology and L-systems;
- materials and crystal search;
- batteries and energy storage;
- semiconductors and AI hardware;
- quantum computing and hybrid optimization;
- aerospace and space science;
- energy, hydrogen and CCUS;
- mining and resource processing;
- industrial engineering and process optimization;
- scientific software and cloud AI.
qFoldIT distinguishes:
- E1 — verified implementation evidence;
- E2 — strong architecture/product evidence;
- E3 — design, roadmap or option evidence;
- EX — third-party/upstream evidence.
Repository size, external ecosystem reach, prospect lists, TAM, gameplay hypotheses and third-party scientific achievements are not automatically qFoldIT-owned value or revenue evidence.
- qFoldIT GitHub organization
- Public project site and STATE
- Canonical Integrated Platform Architecture
- IP, provenance and valuation registry
- UEFN / Fortnite experience
- FoldIT
- MCP standard
qFoldIT
qFoldIT@gmail.com
https://github.com/qfoldit
Built on the open Model Context Protocol (MCP) standard.
Scientific authority remains with validated scientific services and authorized reference boundaries.
The previous organization profile, including its complete historical image set, contact information, links, MPNC material and presentation examples, is retained verbatim in profile/README-LEGACY-2026-08-21.MD.




